Author

J. Borcsok

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:whole-exome sequencing· 3 Assay:whole-genome sequencing· 3 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

I. Csabai· 3 shared M. Diossy· 3 shared O. Rusz· 3 shared S. Spisak· 3 shared V. Tisza· 3 shared Z. Szallasi· 3 shared Z. Sztupinszki· 3 shared M. Krzystanek· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersCancer Biology

I. Csabai

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Author profile →

3 papers

Recent·Most cited

Diagnostic tool to identify and treat DNA repair deficient gastroesophageal adenocarcinomas

A. Prosz, P. Sahgal, C. X. Morris, Z. Sztupinszki, J. Borcsok, M. Diossy, V. Tisza, S. Spisak, O. Rusz, I. Csabai, B. M. Huffman, H. Singh, J.-B. Lazaro, M. Cecchini, J. M. Cleary, , N. S. Sethi

This study identifies HR and NER deficiencies in gastric and esophageal adenocarcinomas and shows their responsiveness to platinum chemotherapy and PARP inhibitors.

bioRxiv · Jul 14, 2022 · PreprintCancer Biology

A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic aberration based molecular signatures

M. Diossy, Z. Sztupinszki, J. Borcsok, M. Krzystanek, V. Tisza, S. Spisak, O. Rusz, J. Timar, I. Csabai, J. Moldvay, A. G. Pedersen, D. Szuts, Z. Szallasi

The paper identifies HRD-associated mutational signatures in lung cancer cases and links them to PARP inhibitor sensitivity and platinum response.

bioRxiv · Nov 28, 2019Cancer Biology

Genomic aberration based molecular signatures efficiently characterize homologous recombination deficiency in prostate cancer

Z. Sztupinszki, M. Diossy, M. Krzystanek, J. Borcsok, M. Pomerantz, V. Tisza, S. Spisak, O. Rusz, I. Csabai, M. Freedman, Z. Szallasi

The paper identifies genomic aberration-based molecular signatures to detect homologous recombination deficiency in prostate cancer, finding that 5-8% of cases may benefit from PARP-inhibitor treatment.

bioRxiv · Jun 24, 2019 · PreprintCancer Biology