Somatostatin peptide signaling dampens cortical circuits and promotes exploratory behavior
Dakota F. Brockway, Keith R. Griffith, Chloe M. Aloimonos, Thomas T. Clarity, J. Brody Moyer, Grace C. Smith, Nigel C. Dao, Md Shakhawat Hossain, Patrick J. Drew, Joshua A. Gordon, David A. Kupferschmidt, Nicole A. Crowley
This study investigates the role of somatostatin peptide signaling in the prelimbic cortex, showing it dampens cortical circuits and promotes exploratory behavior through specific physiological and pharmacological mechanisms.
Cell Reports · Aug 1, 2023Peer-reviewedNeuroscience