Joshua A. Gordon

Altered thalamo-prefrontal synchrony dynamics during spatial working memory task performance in a SETD1A loss-of-function mouse model of schizophrenia predisposition

This study examines how SETD1A loss-of-function affects neural synchrony in mice during a spatial working memory task, finding reduced beta-frequency synchrony between prefrontal cortex and nucleus reuniens.

Activity-induced weakening of hippocampal input to prefrontal VIP interneurons reshapes inhibitory microcircuit function: implications for spatial working memory task acquisition

The paper investigates how hippocampal input to prefrontal VIP interneurons changes with activity and affects spatial working memory task learning in mice.

A consistent map in the medial entorhinal cortex supports spatial memory

The paper shows that a consistent spatial map in the medial entorhinal cortex is necessary for successful spatial memory in mice.

Somatostatin peptide signaling dampens cortical circuits and promotes exploratory behavior

This study investigates the role of somatostatin peptide signaling in the prelimbic cortex, showing it dampens cortical circuits and promotes exploratory behavior through specific physiological and pharmacological mechanisms.

Ventral tegmental area GABA neurons mediate stress-induced anhedonia.

This study shows that VTA GABA neurons drive NAc oscillations during stress, which are necessary and sufficient for stress-induced anhedonia.

Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a mouse model of schizophrenia

The paper investigates how hippocampal CA2 neurons encode social novelty and shows that disrupting this coding in a schizophrenia mouse model can be rescued by a TREK-1 antagonist.

Prelimbic-dependent activation of amygdala somatostatin interneurons signals non-aversive cues to promote discrimination.

This study shows that prelimbic cortex-dependent activation of basolateral amygdala somatostatin interneurons promotes discrimination of non-threatening stimuli by blocking theta-oscillation phase resetting.

Selective Inhibitory Control Of Pyramidal Neuron Ensembles And Cortical Subnetworks By Chandelier Cells

This paper shows that chandelier cells selectively inhibit pyramidal neurons projecting to the basolateral amygdala, shaping communication between cortical networks.