Author

J. C. Blanco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

B. S. Pollard· 1 shared E.-M. Strauch· 1 shared G. A. Prince· 1 shared J. R. Pollard· 1 shared K. J. Gonzalez· 1 shared K. Yim· 1 shared M. S. Boukhvalova· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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1 shared paperImmunology

B. S. Pollard

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2 papers

Recent·Most cited

Systematic computer-aided disulfide design as a general strategy to stabilize prefusion class I fusion proteins

K. J. Gonzalez, K. Yim, J. C. Blanco, M. S. Boukhvalova, E.-M. Strauch

This paper develops a computational method to identify stabilizing disulfide bonds for prefusion class I fusion proteins, demonstrating its effectiveness in stabilizing the RSV F protein and providing protection in a cotton rat model.

bioRxiv · Feb 29, 2024Bioengineering

Classical drug digitoxin inhibits influenza cytokine storm, with implications for COVID-19 therapy.

B. S. Pollard, J. C. Blanco, J. R. Pollard, G. A. Prince

The paper shows that digitoxin reduces cytokine storm in influenza-infected cotton rats, suggesting potential therapeutic use for influenza and coronavirus infections.

bioRxiv · Apr 9, 2020Immunology