Author

K. Yim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Al Hrout· 1 shared B. Peacock· 1 shared E.-M. Strauch· 1 shared H. Schwartz· 1 shared H. Williams· 1 shared J. C. Blanco· 1 shared J. Trepel· 1 shared K. Beebe· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. Al Hrout

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Systematic computer-aided disulfide design as a general strategy to stabilize prefusion class I fusion proteins

K. J. Gonzalez, K. Yim, J. C. Blanco, M. S. Boukhvalova, E.-M. Strauch

This paper develops a computational method to identify stabilizing disulfide bonds for prefusion class I fusion proteins, demonstrating its effectiveness in stabilizing the RSV F protein and providing protection in a cotton rat model.

bioRxiv · Feb 29, 2024Bioengineering

Assessing extracellular vesicles in human biofluids using flow-based analyzers

O. Krzyzaniak, K. Yim, A. Al Hrout, B. Peacock, R. Chahwan

This study compares the performance of two flow-based analyzers for extracellular vesicle phenotyping in human biofluids, finding that nanoFCM accurately analyzes small EVs and identifies underrepresented markers.

bioRxiv · Jul 20, 2022 · PreprintImmunology

HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation

T. Kijima, T. L. Prince, M. Tigue, K. Yim, H. Schwartz, K. Beebe, S. Lee, M. Budzynski, H. Williams, J. Trepel, L. Sistonen, S. K. Calderwood, L. Neckers

This study shows HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction, revealing a noncanonical role for HSP90 in modulating HSF1 activity by removing HSF1 trimers from DNA.

bioRxiv · Mar 2, 2018Biochemistry