J. C. Fung

Reduced Telomerase Interaction with Telomeres Alters Meiotic Chromosome Motion and Gamete Viability

This study shows that reduced telomerase interaction with telomeres in yeast affects meiotic chromosome motion and gamete viability by altering recombination and cytoskeletal forces.

Homologous chromosome recognition via nonspecific interactions

The paper proposes a 'button barcode' model for homologous chromosome recognition, showing that non-specific interactions with non-uniformly distributed sites can achieve high pairing fidelity.

Modeling Cell Biological Features of Meiotic Chromosome Pairing

This paper uses a computational model to study how meiotic chromosome pairing occurs, finding that distributed pairing sites and telomere motion enhance pairing while interlocks resolve through telomere proximity and cooperativity.

Modeling meiotic chromosome pairing: increased fidelity from a tug of war between telomere forces and a pairing-based Brownian ratchet

The paper models meiotic chromosome pairing, showing that telomere forces and a pairing-based Brownian ratchet mechanism enhance pairing fidelity by amplifying affinity differences between homologous and homeologous regions.