J. C. Mejias

This study develops a regenerative immunotherapy using helminth-derived soluble egg antigen to promote tissue repair in multiple injury models.

The paper develops a transfer learning approach to identify senescent cells across species and tissues using an in vivo-derived gene expression signature, revealing conserved and tissue-specific senescence features.

This study shows that age-related senescent T cells promote type 3 immunity, which inhibits tissue repair, and that blocking this pathway improves healing in older animals.

This paper develops a multi-niche microvascularized human bone-marrow-on-a-chip that mimics the hBM microenvironment and shows the endosteal niche's significant contribution to hBM physiology.

The paper characterizes a nanoparticle-in-microgel system for pulmonary drug delivery, focusing on its in-vitro and in-vivo performance to overcome physiologic barriers in the lungs.