Author

J. C. R. Acosta

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Fernandez· 1 shared D. Santamaria· 1 shared E. Molina· 1 shared G. Bretones· 1 shared I. Arechaga· 1 shared J. Leon· 1 shared L. Alonso· 1 shared L. Garcia-Gutierrez· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Fernandez

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1 paper

Recent·Most cited

Cancer BiologybioRxivDec 16, 2018

Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27

J. Leon, L. Garcia-Gutierrez, G. Bretones…·D. Santamaria

The paper shows Myc activates Cdk1 to phosphorylate p27 at Thr187, promoting its degradation and cell cycle progression, with Cdk1 inhibition causing synthetic lethality with Myc.

DOI 10.1038/s41598-019-54917-1

mouseproteomics

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