Author

G. Bretones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Fernandez· 1 shared A. Kleger· 1 shared A. M. Gomez-Valero· 1 shared A. P. Ugalde· 1 shared C. Barcelo· 1 shared C. Crespi· 1 shared C. Steenblock· 1 shared D. Lopez-Garcia· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Fernandez

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Host factor PLAC8 is required for pancreas infection by SARS-CoV-2

L. Ibarguen Gonzalez, S. Heller, M. L. DeDiego, D. Lopez-Garcia, A. M. Gomez-Valero, T. F. Barth, P. Gallego, I. Fernandez-Cardenas, S. Alzate-Pinol, C. Crespi, J. A. Mena-Guerrero, M. E. Cisneros-Barroso, A. P. Ugalde, G. Bretones, C. Steenblock, , C. Barcelo

This study shows that PLAC8 is required for SARS-CoV-2 infection of the pancreas and links pancreatic enzyme levels to COVID-19 severity.

bioRxiv · Aug 18, 2023Cell Biology

Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27

J. Leon, L. Garcia-Gutierrez, G. Bretones, E. Molina, I. Arechaga, J. C. R. Acosta, R. Blanco, A. Fernandez, L. Alonso, P. Sicinski, M. Barbacid, D. Santamaria

The paper shows Myc activates Cdk1 to phosphorylate p27 at Thr187, promoting its degradation and cell cycle progression, with Cdk1 inhibition causing synthetic lethality with Myc.

bioRxiv · Dec 16, 2018Cancer Biology