Author

D. Santamaria

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Carneiro-Figueira· 1 shared A. Fernandez· 1 shared A. Guitian-Caamano· 1 shared A. Varela-Vazquez· 1 shared A. Vidal· 1 shared B. Sanchez-Laorden· 1 shared C. Alabert· 1 shared C. Fernandez-Lozano· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Carneiro-Figueira

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cx43 Enhances Response to BRAF/MEK Inhibitors by Reducing DNA Repair Capacity

A. Varela-Vazquez, A. Guitian-Caamano, P. Carpintero-Fernandez, V. Alvarez, A. Carneiro-Figueira, M. Varela-Eirin, T. Calleja-Chucla, S. Bravo, A. Vidal, J. Sendon-Lago, M. Rodriguez-Candela Mateos, J. R. Caeiro, M. G. Blanco, G. Sabio, C. Rivas, , M. D. Mayan

This study shows that Cx43 enhances the effectiveness of BRAF/MEKi by reducing DNA repair, leading to increased DNA damage and cellular senescence, and proposes a novel therapeutic approach using sEVs.

bioRxiv · Jul 15, 2024Cancer Biology

Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27

J. Leon, L. Garcia-Gutierrez, G. Bretones, E. Molina, I. Arechaga, J. C. R. Acosta, R. Blanco, A. Fernandez, L. Alonso, P. Sicinski, M. Barbacid, D. Santamaria

The paper shows Myc activates Cdk1 to phosphorylate p27 at Thr187, promoting its degradation and cell cycle progression, with Cdk1 inhibition causing synthetic lethality with Myc.

bioRxiv · Dec 16, 2018Cancer Biology