Author

J. Chiffelle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Harari· 3 shared G. Coukos· 3 shared S. Bobisse· 3 shared A. Orcurto· 2 shared C. Sauvage· 2 shared D. Barras· 2 shared D. Dangaj Laniti· 2 shared E. Ghisoni· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. Harari

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tumor-reactive clonotype dynamics underlying clinical response to TIL therapy in melanoma

J. Chiffelle, D. Barras, R. Petremand, A. Orcurto, S. Bobisse, M. Arnaud, A. Auger, B. Navarro Rodrigo, E. Ghisoni, C. Sauvage, D. Saugy, A. Michel, B. Murgues, N. Fahr, M. Imbimbo, , G. Coukos

This study tracks tumor-reactive TIL clonotypes in melanoma patients before and after TIL-ACT to identify factors associated with clinical response.

bioRxiv · Jul 21, 2023 · PreprintCancer Biology

TCRpcDist: Estimating TCR physico-chemical similarity to analyze repertoires and predict specificities

M. A. S. Perez Gomes, J. Chiffelle, S. Bobisse, F. Mayol-Rullan, M. Arnaud, C. Sauvage, G. Coukos, A. Harari, V. Zoete

TCRpcDist clusters TCR repertoires based on physico-chemical properties to predict antigen specificity and identify TCR groups likely to bind similar epitopes.

bioRxiv · Jun 15, 2023Immunology

Tumor Microenvironment Cellular Crosstalk Predicts Response to Adoptive TIL Therapy in Melanoma

D. Barras, E. Ghisoni, J. Chiffelle, A. Orcurto, J. Dagher, N. Fahr, F. Benedetti, I. Crespo, S. Zimmermann, R. Duran, M. Imbimbo, M. Ochoa De Olza, B. Navarro, K. Homiscko, S. Bobisse, , G. Coukos

This study identifies CD8+ TIL-myeloid cell networks as predictors of response to adoptive TIL therapy in melanoma using single-cell RNA-seq and spatial proteomic analyses.

bioRxiv · Dec 23, 2022 · PreprintImmunology