R. Duran

Patient-derived lymphomoids preserve the tumor architecture and allow to assess response to therapies in lymphoma

This study develops lymphomoids from patient lymphoma samples to assess therapy response, showing consistency with clinical outcomes.

Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation.

The paper identifies two new divisome members in Corynebacteriales and shows their role in coordinating cell division and polar elongation with the divisome and elongasome.

Tumor Microenvironment Cellular Crosstalk Predicts Response to Adoptive TIL Therapy in Melanoma

This study identifies CD8+ TIL-myeloid cell networks as predictors of response to adoptive TIL therapy in melanoma using single-cell RNA-seq and spatial proteomic analyses.

Phosphorylation of aldose-6-phosphate reductase from Prunus persica leaves

This study shows that Ald6PRase from peach leaves is phosphorylated in planta and that phosphorylation can regulate its activity.

Structural basis of flagellar filament asymmetry and supercoil templating by Leptospira spirochete sheath proteins

This study solves cryo-EM structures of Leptospira flagellar filaments, revealing how sheath proteins induce supercoiling and motility through distinct functional roles.

A TPR scaffold couples signal detection to OdhI phosphorylation in metabolic control by the protein kinase PknG

This study identifies a TPR scaffold in PknG that links signal detection to OdhI phosphorylation, regulating metabolic control in actinobacteria.

Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response.

This study uses proteomics to show that PknG knockout in M. tuberculosis alters the proteome, affecting cell envelope biosynthesis and hypoxia response.

Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum

This study investigates the essential interaction between FtsZ and SepF in C. glutamicum, revealing their dynamic roles in Z-ring and septum formation through structural and functional analyses.