A. Harari

KIR3DL1 and Tox identify clonally expanded encephalitogenic neuron-specific CD8+ T cells in autoimmune encephalitis

The paper identifies clonally expanded neuron-specific CD8+ T cells in anti-Ri AIE patients using an unbiased approach and shows they express KIR3DL1 and TOX.

Tumor-reactive clonotype dynamics underlying clinical response to TIL therapy in melanoma

This study tracks tumor-reactive TIL clonotypes in melanoma patients before and after TIL-ACT to identify factors associated with clinical response.

TCRpcDist: Estimating TCR physico-chemical similarity to analyze repertoires and predict specificities

TCRpcDist clusters TCR repertoires based on physico-chemical properties to predict antigen specificity and identify TCR groups likely to bind similar epitopes.

Tumor Microenvironment Cellular Crosstalk Predicts Response to Adoptive TIL Therapy in Melanoma

This study identifies CD8+ TIL-myeloid cell networks as predictors of response to adoptive TIL therapy in melanoma using single-cell RNA-seq and spatial proteomic analyses.

Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes

The paper predicts MHC-II epitope specificities using machine learning, revealing a reverse binding mode in ligands across multiple species.

Intense sexual conflict affects the female choice strategy in the gregarious desert locust

The paper investigates how intense sexual conflict influences female choice strategies in gregarious desert locusts but has been withdrawn due to disputes over result interpretation.

Males perceive honest information from female released sex pheromone in a moth

The paper shows that female moths convey honest information about their quality through sex pheromone blends, which males use to select mates.

Integrated Proteogenomic Deep Sequencing and Analytics Accurately Identify Non-Canonical Peptides in Tumor Immunopeptidomes

The paper develops an MS-based proteogenomic approach to identify non-canonical HLA peptides in tumors, finding hundreds of shared and tumor-specific peptides, including an immunogenic one from ABCB5.

Open source computational simulation for a moth-inspired navigation algorithm

This paper introduces MothPy, an open-source simulation framework for testing moth-inspired navigation strategies in turbulent odor plumes.

Deep motif deconvolution of HLA-II peptidomes for robust class II epitope predictions

The paper improves HLA-II epitope prediction by combining mass spectrometry data with a new motif deconvolution algorithm, enhancing motif definition and prediction accuracy.

Precopulatory behavior and sexual conflict in the desert locust

This study describes the precopulatory behavior of desert locusts, identifying sexual conflict and novel behaviors in both sexes.