Author

J. Courtois

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Sauvat· 1 shared B. E Silva· 1 shared C. Durette· 1 shared C. Perreault· 1 shared F. Baron· 1 shared G. Ehx· 1 shared J. Humeau· 1 shared J. Lanoix· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Sauvat

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1 paper

Recent·Most cited

Autophagy degrades immunogenic endogenous retroelements induced by 5-azacytidine in acute myeloid leukemia

N. Noronha, C. Durette, B. E Silva, J. Courtois, J. Humeau, A. Sauvat, M.-P. Hardy, K. Vincent, J.-P. Laverdure, J. Lanoix, F. Baron, P. Thibault, C. Perreault, G. Ehx

This study shows that 5-azacytidine induces endogenous retroelement transcripts in AML cells, which are degraded by autophagy and not presented as MHC-I peptides, and that autophagy inhibition enhances immune responses.

Leukemia · Apr 16, 2024Peer-reviewedImmunology