Author

J. Humeau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

C. Durette· 2 shared C. Perreault· 2 shared J. Lanoix· 2 shared J.-P. Laverdure· 2 shared K. Vincent· 2 shared P. Thibault· 2 shared A. Sauvat· 1 shared A. Trofimov· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

C. Durette

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Author profile →

2 papers

Recent·Most cited

Autophagy degrades immunogenic endogenous retroelements induced by 5-azacytidine in acute myeloid leukemia

N. Noronha, C. Durette, B. E Silva, J. Courtois, J. Humeau, A. Sauvat, M.-P. Hardy, K. Vincent, J.-P. Laverdure, J. Lanoix, F. Baron, P. Thibault, C. Perreault, G. Ehx

This study shows that 5-azacytidine induces endogenous retroelement transcripts in AML cells, which are degraded by autophagy and not presented as MHC-I peptides, and that autophagy inhibition enhances immune responses.

Leukemia · Apr 16, 2024Peer-reviewedImmunology

Transposable elements regulate thymus development and function

J.-D. Larouche, C. M. Laumont, A. Trofimov, K. Vincent, L. Hesnard, S. Brochu, C. Cote, J. Humeau, E. Bonneil, J. Lanoix, C. Durette, P. Gendron, J.-P. Laverdure, E. R. Richie, S. Lemieux, , C. Perreault

This study investigates the role of transposable elements in thymus development and function, showing their interactions with transcription factors and their impact on T-cell tolerance.

bioRxiv · Jul 12, 2023Immunology