The nucleus bypasses obstacles by deforming like a drop with surface tension mediated by lamin A/C
A. Katiyar, J. Zhang, J. D. Antani, Y. Yu, K. L. Scott, P. P. Lele, C. A. Reinhart-King, N. J. Sniadecki, K. J. Roux, R. B. Dickinson, T. P. Lele
The paper shows lamin A/C enables nuclear deformation through fibrous environments by acting like surface tension, allowing nuclei to bypass obstacles without rupturing.
bioRxiv · Mar 10, 2022 · PreprintCell Biology