Author

J. D. Carelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

J. Taunton· 2 shared A. Brown· 1 shared A. Ferguson· 1 shared E. J. Rundlet· 1 shared H.-Y. Wang· 1 shared K. Oltion· 1 shared M. F. Juette· 1 shared M. Holm· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

J. Taunton

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2 papers

Recent·Most cited

Didemnin B and ternatin-4 inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes

M. F. Juette, J. D. Carelli, E. J. Rundlet, A. Brown, S. Shao, A. Ferguson, M. R. Wasserman, M. Holm, J. Taunton, S. C. Blanchard

This study shows how didemnin B and ternatin-4 inhibit translation by trapping eEF1A in a GTPase-activated conformation using single-molecule imaging and cryo-EM.

bioRxiv · Aug 1, 2022 · PreprintBiochemistry

An E3 ligase network engages GCN1 to promote elongation factor-1α degradation on stalled ribosomes

K. Oltion, J. D. Carelli, T. Yang, S. K. See, H.-Y. Wang, M. Kampmann, J. Taunton

The paper identifies an E3 ligase network that promotes eEF1A degradation on stalled ribosomes through interaction with GCN1.

bioRxiv · Mar 21, 2022 · PreprintCell Biology