Author

K. Oltion

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J. Taunton· 2 shared A. A. Q. Al-Khdhairawi· 1 shared D. Ruggero· 1 shared H. Tom· 1 shared H. Wang· 1 shared H. Yang· 1 shared H.-Y. Wang· 1 shared J. D. Carelli· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

J. Taunton

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Author profile →

2 papers

Recent·Most cited

An E3 ligase network engages GCN1 to promote elongation factor-1α degradation on stalled ribosomes

K. Oltion, J. D. Carelli, T. Yang, S. K. See, H.-Y. Wang, M. Kampmann, J. Taunton

The paper identifies an E3 ligase network that promotes eEF1A degradation on stalled ribosomes through interaction with GCN1.

bioRxiv · Mar 21, 2022 · PreprintCell Biology

Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumor eEF1A antagonist SR-A3

H. Wang, H. Yang, M. Holm, K. Oltion, H. Tom, A. A. Q. Al-Khdhairawi, J.-F. F. Weber, S. Blanchard, D. Ruggero, J. Taunton

This study synthesizes and characterizes SR-A3, a stereoisomer of a natural product, showing enhanced binding kinetics and therapeutic efficacy in a mouse lymphoma model.

bioRxiv · Oct 6, 2020Pharmacology & Toxicology