Author

J. D. Knight

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

H. Lin· 2 shared A. A. Alnaas· 1 shared A. E. Matthews· 1 shared A. H. Beaven· 1 shared A. J. Sodt· 1 shared A. Watson-Siriboe· 1 shared C. Michel· 1 shared C. T. Shearn· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

H. Lin

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2 papers

Recent·Most cited

Synaptotagmin 7 C2 domains induce membrane curvature stress via electrostatic interactions and the wedge mechanism

A. H. Beaven, V. Bikkumalla, N. L. Chon, A. E. Matthews, H. Lin, J. D. Knight, A. J. Sodt

This study investigates how Syt-7 C2 domains generate membrane curvature through electrostatic interactions and the wedge mechanism, using simulations and assays.

bioRxiv · Jan 10, 2024 · PreprintBiophysics

Multivalent lipid targeting by the calcium-independent C2A domain of Slp-4/granuphilin

A. A. Alnaas, A. Watson-Siriboe, S. Tran, M. Negussie, J. A. Henderson, J. R. Osterberg, N. Lee Chon, J. Oviedo, T. Lyakhova, C. Michel, N. Reisdorph, R. Reisdorph, C. T. Shearn, H. Lin, J. D. Knight

This study shows that the Slp-4 C2A domain binds PIP2 with high affinity through multivalent interactions involving both specific and nonspecific lipid contacts.

bioRxiv · May 29, 2020 · PreprintBiophysics