Human marginal zone B cell development from early T2 progenitors
T. J. Tull, M. J. Pitcher, W. Guesdon, J. H. Siu, C. Lebrero-Fernandez, Y. Zhao, N. Petrov, S. Heck, R. Ellis, P. Dhami, U. D. Kadolsky, M. Kleeman, Y. Kamra, D. J. Fear, S. John, , J. Spencer
The paper identifies an IgMhi developmental trajectory in human B cell maturation that connects T2 progenitors to marginal zone B cells and links its disruption to severe SLE.
bioRxiv · Sep 24, 2020Cell Biology