C. Magnan

Long-term disruption of glucose homeostasis in a rodent model of preterm birth.

This study investigates the long-term metabolic effects of perinatal inflammation in mice, finding sex-dependent glucose metabolism dysregulation and potential therapeutic implications.

Improved Glucose Homeostasis Following Vertical Sleeve Gastrectomy is Associated with Alternate Wiring of the Liver Molecular Clock in a Rat Model of Spontaneously-Occurring Type 2 Diabetes

This study shows that vertical sleeve gastrectomy alters the liver molecular clock in rats with type 2 diabetes, improving glucose homeostasis through changes in circadian rhythms and metabolism.

A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion

This study shows that GLP-1 receptor activation in the olfactory bulb enhances insulin secretion via a sympathetic pathway involving the paraventricular nucleus.

Investigating pathogenicity and virulence of Staphylococcus pettenkoferi: an emerging pathogen

This study compares the pathogenicity of Staphylococcus pettenkoferi to Staphylococcus aureus using in vitro, ex vivo, and in vivo assays, revealing its ability to survive in human cells and cause zebrafish embryo mortality.

Hepatocyte serine palmitoyl transferase 2 deficiency promotes liver C16:0-ceramide accumulation through sphingomyelin hydrolysis and leads to liver damage and dysfunction in mice

This study shows that Sptlc2 deficiency in hepatocytes increases liver ceramide levels via sphingomyelin hydrolysis, leading to liver damage, dysfunction, and metabolic changes in mice.

The Microbial Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function

This study identifies 4-cresol as a microbial metabolite that improves glucose homeostasis and β-cell function in preclinical models of cardiometabolic disease.

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota

The paper demonstrates that gut microbiota can convert trimethylamine N-oxide (TMAO) back to trimethylamine (TMA), which is then absorbed by the host and reconverted to TMAO, highlighting a metabolic retroconversion process.