Author

J. D. Stockton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Beggs· 1 shared A. D. Beggs· 1 shared A. Stodolna· 1 shared B. Noyvert· 1 shared C. Bryer· 1 shared C. M. Whalley· 1 shared C. Yau· 1 shared I. Pentland· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Beggs

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Patient derived organoids reveal that PI3K/AKT signaling is an escape pathway for radioresistance and a target for therapy in rectal cancer.

K. Wanigasooriya, J. D. Barros-Silva, L. Tee, M. E. Elasrag, A. Stodolna, O. Pickles, J. D. Stockton, C. Bryer, R. Hoare, C. M. Whalley, R. Tyler, T. Sillo, C. Yau, T. Ismail, A. D. Beggs

The paper identifies PI3K/AKT/mTOR pathway upregulation as a mechanism of radioresistance in rectal cancer and shows that dual PI3K/mTOR inhibitors radiosensitize cancer cells in organoid models.

bioRxiv · Aug 31, 2021 · PreprintCancer Biology

The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expression

J. Ferguson, K. Campos-Leon, I. Pentland, J. D. Stockton, T. Günther, A. Beggs, S. Roberts, B. Noyvert, J. L. Parish

This paper shows CTCF regulates HPV18 transcript splicing and late gene expression during differentiation by controlling chromatin looping and splice site usage.

bioRxiv · Apr 30, 2021Microbiology