Intermediate Filaments Associate with Aggresome-like Structures in Proteostressed C. elegans Neurons and Influence Large Vesicle Extrusions as Exophers
M. L. Arnold, J. F. Cooper, R. Androwski, S. Ardeshna, I. Melentijevic, A. J. Smart, R. J. Guasp, K. C. Nguyen, G. Bai, D. H. Hall, B. D. Grant, M. Driscoll
This study shows that intermediate filaments in C. elegans neurons form aggresome-like structures under proteostress and influence exopher production for aggregate removal.
bioRxiv · Aug 3, 2022 · PreprintCell Biology