ImmunologybioRxiv
Charcot-Leyden Crystals activate the NLRP3 inflammasome and cause IL-1β inflammation
J. F. Rodrigues-Alcazar, M. A. Ataide, G. Engels…·B. S. Franklin
This study shows that Charcot-Leyden crystals activate the NLRP3 inflammasome, leading to IL-1β release and inflammation in vitro and in vivo.