Author

W. Kastenmueller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

N. Garbi· 2 shared A. M. Mansilla· 1 shared A. Oener· 1 shared A. S. Brown· 1 shared A. Zernecke-Madsen· 1 shared B. Ghesquiere· 1 shared B. S. Franklin· 1 shared C. Schmitt-Mabmunyo· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

N. Garbi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Opposing roles of resident and infiltrating immune cells in the defence against Legionella longbeachae via IL-18R/IFN-γ/ROS axis

L. M. Oberkircher, V. M. Scheiding, H. L. Rafeld, E. Hanssen, J. N. Hansen, M. J. Fleischmann, N. M. Kessler, D. Pitsch, D. Wachten, W. Kastenmueller, A. S. Brown, E. Hartland, I. R. van Driel, G. Z. Ng, N. Garbi

This study identifies opposing roles of tissue-resident alveolar macrophages and infiltrating neutrophils/monocyte-derived cells in controlling Legionella longbeachae infection via the IL-18R/IFN-γ/ROS pathway.

bioRxiv · Jan 31, 2024 · PreprintImmunology

HIF-1α-mediated mitochondrial-glycolytic reprogramming controls the transition of precursor to terminally exhausted T cells

H. Wu, X. Zhao, S. M. Hochrein, M. Eckstein, G. F. Gubert, K. Knoepper, A. M. Mansilla, A. Oener, R. Doucet-Ladeveze, W. Schmitz, B. Ghesquiere, S. Theurich, J. Dudek, G. Gasteiger, A. Zernecke-Madsen, , M. Vaeth

This study identifies HIF-1α-mediated metabolic reprogramming as a mechanism controlling the transition of precursor T cells to terminally exhausted T cells in chronic infections and cancer.

bioRxiv · Aug 31, 2023 · PreprintImmunology

Charcot-Leyden Crystals activate the NLRP3 inflammasome and cause IL-1β inflammation

J. F. Rodrigues-Alcazar, M. A. Ataide, G. Engels, C. Schmitt-Mabmunyo, N. Garbi, W. Kastenmueller, E. Latz, B. S. Franklin

This study shows that Charcot-Leyden crystals activate the NLRP3 inflammasome, leading to IL-1β release and inflammation in vitro and in vivo.

bioRxiv · Jan 25, 2018Immunology