J. Gordy

An intranasal stringent response vaccine targeting dendritic cells as a novel adjunctive therapy against tuberculosis

This paper develops a DNA vaccine targeting dendritic cells that enhances isoniazid efficacy against tuberculosis by inducing strong immune responses and reducing Mtb burden.

A Vaccine Composed of Antigen Fused to a Ligand for a Receptor on Immature Dendritic Cells Elicits Elevated Antibody Responses to Malaria Sporozoites in Infant Macaques

This study shows that a malaria vaccine with a specific antigen and adjuvant induces strong antibody responses in infant macaques, reducing sporozoite load and suggesting potential for human use.

IFN-alpha and 5-Aza-2-deoxycytidine enhance the anti-tumor efficacy of a dendritic-cell targeting MIP3alpha-Gp100-Trp2 DNA vaccine by affecting T-cell recruitment and tumor microenvironment gene expression

This paper shows that combining IFN-alpha and 5-Aza-2-deoxycytidine with a MIP3alpha-Gp100-Trp2 DNA vaccine improves anti-tumor efficacy by enhancing T-cell recruitment and altering tumor microenvironment gene expression.