Author

P. Karakousis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Organism:human· 1

Frequent Co-Authors

A. Braxton· 1 shared A. Jedlicka· 1 shared A. Johanson· 1 shared A. Pekosz· 1 shared A. Sandhu· 1 shared C. Brayton· 1 shared C. Danchik· 1 shared C. Schill· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPathology

A. Braxton

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

An intranasal stringent response vaccine targeting dendritic cells as a novel adjunctive therapy against tuberculosis

S. Karanika, J. Gordy, P. Neupane, T. KARANTANOS, J. Castillo, D. Quijada, K. Comstock, A. Sandhu, Y. Hui, S. Ayeh, R. Tasneen, S. Krug, C. Danchik, T. Wang, C. Schill, , P. Karakousis

This paper develops a DNA vaccine targeting dendritic cells that enhances isoniazid efficacy against tuberculosis by inducing strong immune responses and reducing Mtb burden.

bioRxiv · Apr 19, 2022Immunology

Progression and Resolution of SARS-1 CoV-2 Infection in Golden Syrian Hamsters

K. Mulka, S. Beck, C. Solis, A. Johanson, S. Queen, M. McCarron, M. Richardson, R. Zhou, P. Marinho, A. Jedlicka, S. Guerrero-Martin, E. Shirk, A. Braxton, J. Brockhurst, P. Creisher, , J. Mankowski

This study tracks SARS-CoV-2 infection progression in golden Syrian hamsters, showing weight loss, lung damage, and resolution over time.

bioRxiv · Jun 25, 2021Pathology

The anti-tubercular activity of simvastatin is mediated by cholesterol-dependent regulation of autophagy via the AMPK-mTORC1-TFEB axis

N. Bruiners, N. K. Dutta, V. Guerrini, H. Salamon, K. Yamaguchi, P. Karakousis, M. L. Gennaro

This study shows simvastatin's anti-tubercular effect is due to cholesterol inhibition, which activates AMPK, blocks mTORC1, and promotes TFEB-driven autophagy.

bioRxiv · Mar 4, 2020Immunology