Author

J. Grau-Exposito

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1

Frequent Co-Authors

M. Genesca· 5 shared M. J. Buzon· 5 shared D. Perea· 3 shared V. Falco· 2 shared A. Astorga-Gamaza· 1 shared A. Curran· 1 shared A. Dolinar· 1 shared A. Esteve-Codina· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersImmunology

M. Genesca

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells

M. Kobayashi-Ishihara, K. F. Smutna, F. E. Alonso, J. Argilaguet, A. Esteve-Codina, K. Geiger, M. Genesca, J. Grau-Exposito, C. Duran-Castells, S. Rogenmoser, R. Böttcher, J. Jungfleisch, B. Oliva, J. P. Martinez, M. Li, , A. Meyerhans

This study identifies SLFN12 as an HIV-1 restriction factor that inhibits viral replication and reactivation through codon-usage dependent post-transcriptional block in CD4+ T cells.

bioRxiv · Nov 9, 2022Immunology

Zinc pyrithione is a potent inhibitor of PLPro and cathepsin L enzymes with ex vivo inhibition of SARS-CoV-2 entry and replication

J. Kladnik, A. Dolinar, J. Kljun, D. Perea, J. Grau-Exposito, M. Genesca, M. Novinec, M. J. Buzon, I. Turel

bioRxiv · Mar 3, 2022Biochemistry

Identification of HIV-Reservoir Cells with Reduced Susceptibility to Antibody-Dependent Immune Response

A. Astorga-Gamaza, J. Grau-Exposito, J. Burgos, J. Navarro, A. Curran, B. Planas, P. Suanzes, V. Falco, M. Genesca, M. J. Buzon

The paper identifies HIV-infected cells expressing CD32 as having reduced susceptibility to NK-mediated antibody-dependent cell cytotoxicity, contributing to viral persistence.

bioRxiv · Feb 24, 2022Immunology

Entrectinib - a SARS-CoV-2 inhibitor in Human Lung Tissue (HLT) cells

A. Peralta-Garcia, M. Torrens-Fontanals, T. M. Stepniewski, J. Grau-Exposito, D. Perea, V. Ayinampudi, M. Waldhoer, M. Zimmermann, M. J. Buzon, M. Genesca, J. Selent

This study identifies entrectinib as a potential antiviral drug against SARS-CoV-2 using drug repurposing, virtual screening, and in vitro assays in Human Lung Tissue cells.

bioRxiv · Sep 7, 2021Cell Biology

Evaluation of SARS-CoV-2 Entry, Inflammation and New Therapeutics in Human Lung Tissue Cells

J. Grau-Exposito, D. Perea, M. Suppi, N. Massana, A. Vergara, M. J. Soler, J. Blanco, B. Trinite, J. Garcia-Perez, J. Alcami, A. Serrano-Mollar, J. Rosado, V. Falco, M. Genesca, M. J. Buzon

This paper develops a method using primary human lung tissue cells to study SARS-CoV-2 entry, inflammation, and therapeutics, identifying new drug candidates and showing interferons do not modulate ACE2 expression.

bioRxiv · Apr 21, 2021Microbiology