Author

J. H. A. Martens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M. Vermeulen· 2 shared A. Ahmed· 1 shared A. Krippner-Heidenreich· 1 shared A. Mandoli· 1 shared A. Vyakarnam· 1 shared B. A. van der Reijden· 1 shared B. Geckin· 1 shared B. Kim· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

M. Vermeulen

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 7, 2023

The neuronal homeobox transcription factor HMX3 is a crucial vulnerability factor in MECOM-negative KMT2A::MLLT3 acute myelomonocytic leukemia

S. Arza-Apalategi, B. M. H. Heuts, S. M. Bergevoet…·B. A. van der Reijden

The paper identifies HMX3 as a critical vulnerability in MECOM-negative KMT2A::MLLT3 AML, showing it promotes proliferation and blocks differentiation.

DOI 10.1101/2023.11.07.565950

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 30, 2022

Differences in anti-viral immune responses in individuals of Indian and European origin: relevance for the COVID-19 pandemic

B. Geckin, M. Zoodsma, G. Kilic…·M. G. Netea

The paper compares anti-viral immune responses between individuals of Indian and European origin, finding differences in chromatin accessibility and transcriptional responses to viral stimulation, which may explain variations in COVID-19 susceptibility.

DOI 10.1101/2022.08.30.505791

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivOct 29, 2018

CBFβ-MYH11 interferes with megakaryocyte differentiation via modulating a gene program that includes GATA2 and KLF1

G. Yi, A. Mandoli, L. Jussen…·J. H. A. Martens

This study shows that the CBFβ-MYH11 fusion protein inhibits megakaryocyte differentiation by disrupting the GATA2 and KLF1 gene program in inv(16) AML cells.

DOI 10.1038/s41408-019-0194-8

humanbulk RNA-seq

𝕏 PostBluesky