PhysiologybioRxivPreprint
Peripheral sgp130-mediated trans-signaling blockade induces obesity and insulin resistance in mice via PPARα suppression
T. Lanton, O. Levkovitch-Siany, S. Udi…·J. H. Axelrod
This study shows that blocking peripheral sgp130-mediated trans-signaling in mice causes obesity and insulin resistance by suppressing PPARα.
DOI 10.1101/2020.09.24.309716