Author

J. H. Dupuis

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. B. Suryawanshi· 1 shared A. Deshmukh· 1 shared A. Gustchina· 1 shared A. Wlodawer· 1 shared D. D. Lorimer· 1 shared H. Xiao· 1 shared I. Rathore· 1 shared J. Abendroth· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. B. Suryawanshi

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1 paper

Recent·Most cited

Structures of plasmepsin X from P. falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme

p. kesari, A. Deshmukh, N. Pahelkar, A. B. Suryawanshi, I. Rathore, V. Mishra, J. H. Dupuis, H. Xiao, A. Gustchina, J. Abendroth, M. Labaied, R. Y. Yada, A. Wlodawer, T. E. Edwards, D. D. Lorimer, P. Bhaumik

The paper reports the crystal structure of PfPMX zymogen, revealing a novel inactivation mechanism and molecular basis for inhibitor binding in the mature enzyme.

bioRxiv · Sep 24, 2021Biophysics