Cancer BiologybioRxiv
The Establishment of CDK9/ RNA PolII/H3K4me3/DNA Methylation Feedback Promotes HOTAIR Expression by RNA Elongation Enhancement in Cancer
C. H. Wong, C. H. Li, Q. He…·Y. Chen
The paper identifies a positive feedback loop involving CDK9, histone modification, and DNA methylation that enhances HOTAIR expression through transcription elongation in cancer.
DOI 10.1016/j.ymthe.2022.01.038