Author

C. H. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

K.-F. To· 3 shared Y. Chen· 3 shared C. H. Li· 2 shared J. H.-M. Tong· 2 shared Q. He· 2 shared S. L. Chan· 2 shared C. Kuhlberg· 1 shared C. Qian· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

K.-F. To

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Genome-scale requirements for dynein-based trafficking revealed by a high-content arrayed CRISPR screen

C. H. Wong, S. Wingett, C. Qian, M. Taliaferro, D. Ross-Thriepland, S. L. Bullock

The paper uses a CRISPR screen to identify genes critical for dynein-based trafficking, revealing novel regulators and functional relationships in microtubule transport.

bioRxiv · Mar 1, 2023 · PreprintCell Biology

Subgenomic RNAs as molecular indicators of asymptomatic SARS-CoV-2 infection

C. H. Wong, C. Y. Ngan, R. L. Goldfeder, J. Idol, C. Kuhlberg, R. Maurya, K. Kelly, G. Omerza, N. Renzette, F. D. Abreu, L. Li, F. A. Browne, E. T. Liu, C.-L. Wei

The paper examines subgenomic RNA (sgRNA) expression and structural variations in symptomatic and asymptomatic SARS-CoV-2 infections to correlate with disease severity.

bioRxiv · Feb 6, 2021 · PreprintMicrobiology

Ectopic HOTTIP Expression Induces Non-canonical Transactivation Pathways to Promote Growth and Invasiveness in Pancreatic Ductal Adenocarcinoma

C. H. Wong, C. H. Li, Q. He, S. L. Chan, J. H.-M. Tong, K.-F. To, Y. Chen

This study identifies HOTTIP's role in promoting pancreatic ductal adenocarcinoma through both canonical HOXA13-mediated and non-canonical WDR5-MLL1-H3K4me3 pathways.

bioRxiv · Oct 21, 2019Cancer Biology

The Establishment of CDK9/ RNA PolII/H3K4me3/DNA Methylation Feedback Promotes HOTAIR Expression by RNA Elongation Enhancement in Cancer

C. H. Wong, C. H. Li, Q. He, J. H. M. Tong, K.-F. To, Y. Chen

The paper identifies a positive feedback loop involving CDK9, histone modification, and DNA methylation that enhances HOTAIR expression through transcription elongation in cancer.

bioRxiv · Oct 21, 2019Cancer Biology

CircFOXK2 Promotes Tumor Growth and Metastasis of Pancreatic Ductal Adenocarcinoma via Complexing with RNA Binding Proteins and Sponging MiR-942

C. H. Wong, U. K. Lou, Y. Li, S. L. Chan, J. H.-M. Tong, K.-F. To, Y. Chen

This study identifies circFOXK2 as an oncogenic circRNA in PDAC that promotes tumor growth and metastasis by acting as a miR-942 sponge and interacting with RNA-binding proteins.

bioRxiv · Oct 3, 2019Cancer Biology