Author

K.-F. To

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. H. Wong· 3 shared Y. Chen· 3 shared C. H. Li· 2 shared J. H.-M. Tong· 2 shared Q. He· 2 shared S. L. Chan· 2 shared J. H. M. Tong· 1 shared U. K. Lou· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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3 shared papersCancer Biology

C. H. Wong

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ectopic HOTTIP Expression Induces Non-canonical Transactivation Pathways to Promote Growth and Invasiveness in Pancreatic Ductal Adenocarcinoma

C. H. Wong, C. H. Li, Q. He, S. L. Chan, J. H.-M. Tong, K.-F. To, Y. Chen

This study identifies HOTTIP's role in promoting pancreatic ductal adenocarcinoma through both canonical HOXA13-mediated and non-canonical WDR5-MLL1-H3K4me3 pathways.

bioRxiv · Oct 21, 2019Cancer Biology

The Establishment of CDK9/ RNA PolII/H3K4me3/DNA Methylation Feedback Promotes HOTAIR Expression by RNA Elongation Enhancement in Cancer

C. H. Wong, C. H. Li, Q. He, J. H. M. Tong, K.-F. To, Y. Chen

The paper identifies a positive feedback loop involving CDK9, histone modification, and DNA methylation that enhances HOTAIR expression through transcription elongation in cancer.

bioRxiv · Oct 21, 2019Cancer Biology

CircFOXK2 Promotes Tumor Growth and Metastasis of Pancreatic Ductal Adenocarcinoma via Complexing with RNA Binding Proteins and Sponging MiR-942

C. H. Wong, U. K. Lou, Y. Li, S. L. Chan, J. H.-M. Tong, K.-F. To, Y. Chen

This study identifies circFOXK2 as an oncogenic circRNA in PDAC that promotes tumor growth and metastasis by acting as a miR-942 sponge and interacting with RNA-binding proteins.

bioRxiv · Oct 3, 2019Cancer Biology