Author

J. H. Martens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Carrasco· 1 shared A. Illendula· 1 shared A. Melnick· 1 shared A. Vilas-Zornoza· 1 shared A. Visser· 1 shared B. Paiva· 1 shared C. Boiers· 1 shared C. Meydan· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Carrasco

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell cycle corruption in a preleukemic ETV6-RUNX1 model exposes RUNX1 addiction as a therapeutic target in acute lymphoblastic leukemia

J. P. Wray, E. M. Deltcheva, C. Boiers, S. E. Richardson, J. B. Chhetri, S. Gagrica, Y. Guo, A. Illendula, J. H. Martens, H. H. Stunnenberg, J. H. Bushweller, R. Nimmo, T. Enver

This study shows that RUNX1 addiction is a therapeutic target in acute lymphoblastic leukemia, as inhibiting RUNX1 activity spares normal hematopoiesis and affects multiple genetic subtypes.

bioRxiv · Dec 22, 2020 · PreprintCancer Biology

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

R. Ordonez, M. Kulis, N. Russinol, V. Chapaprieta, R. Beekman, C. Meydan, M. Duran-Ferrer, N. Verdaguer-Dot, G. Clot, R. Vilarrasa-Blasi, L. Garate, E. Miranda, A. Carrasco, T. Ezponda, A. Vilas-Zornoza, , J. I. Martin-Subero

The paper identifies aberrant chromatin activation as a common mechanism driving the malignant phenotype in multiple myeloma.

bioRxiv · Aug 20, 2019Cancer Biology

Large-scale in-vitro production of red blood cells from human peripheral blood mononuclear cells

S. J. Heshusius, E. Heideveld, P. Burger, M. Thiel-Valkhof, E. Sellink, E. Varga, E. Ovchynnikova, A. Visser, J. H. Martens, M. M. von Lindern, E. M. van den Akker

This study develops a scalable method to produce red blood cells from peripheral blood mononuclear cells, achieving high yields and functional maturity comparable to in vivo cells.

bioRxiv · Jun 18, 2019Cell Biology