Author

T. Ezponda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2

Frequent Co-Authors

A. Vilas-Zornoza· 3 shared D. Lara-Astiaso· 3 shared F. Prosper· 3 shared B. Paiva· 2 shared D. Dupere-Richer· 2 shared J. D. Licht· 2 shared J. I. Martin-Subero· 2 shared M. Hernaez· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

A. Vilas-Zornoza

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

KDM6A Regulates Immune Response Genes in Multiple Myeloma

D. Dupere-Richer, A. Riva, S. Maji, B. G. Barwick, H. Casella, A. Sobh, G. Quickstad, J. Li, u. de, C. Piper, M. Kulis, T. Ezponda, I. Martin-Subero, G. Tonon, W. Zhang, , J. D. Licht

This study shows KDM6A regulates immune response genes in multiple myeloma by activating NLRC5 and CIITA, and its loss reduces MHC expression, which can be reversed by HDAC3 inhibitors.

bioRxiv · Feb 12, 2024Cancer Biology

Uncovering the regulatory landscape of early human B-cell lymphopoiesis and its implications in the pathogenesis of B-cell acute lymphoblastic leukemia

N. Planell, X. Martinez-de-Morentin, D. Mouzo, D. Lara-Astiaso, A. Vilas-Zornoza, P. San Martin-Uriz, D. Alignani, B. Paiva, A. Maillo, A. Kurowska, N. Berastegui, P. Garcia-Olloqui, A. Urdangarin, P. Noori, A. Ortega-Legarreta, , D. Gomez-Cabrero

This study characterizes the gene regulatory network of early human B-cell development and identifies regulatory elements linked to B-cell acute lymphoblastic leukemia.

bioRxiv · Jul 1, 2023 · PreprintImmunology

Transcriptional regulation of HSCs in Aging and MDS reveals DDIT3 as a Potential Driver of Dyserythropoiesis

N. Berastegui, M. Ainciburu, J. P. Romero, A. Alfonso-Pierola, C. Philippe, A. Vilas-Zornoza, P. San Martin, R. Ordonez, D. O. Alignani, S. Sarvide, L. Castro, J. M. Lamo-Espinosa, M. San-Julian, T. Jimenez, F. Lopez Cardenas, , F. Prosper

This study identifies DDIT3 as a driver of dyserythropoiesis in MDS by showing its upregulation in HSCs and its ability to disrupt erythropoiesis when overexpressed.

bioRxiv · Sep 8, 2021 · PreprintCancer Biology

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

R. Ordonez, M. Kulis, N. Russinol, V. Chapaprieta, R. Beekman, C. Meydan, M. Duran-Ferrer, N. Verdaguer-Dot, G. Clot, R. Vilarrasa-Blasi, L. Garate, E. Miranda, A. Carrasco, T. Ezponda, A. Vilas-Zornoza, , J. I. Martin-Subero

The paper identifies aberrant chromatin activation as a common mechanism driving the malignant phenotype in multiple myeloma.

bioRxiv · Aug 20, 2019Cancer Biology