Author

J. Halkias

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

G. K. Fragiadakis· 2 shared T. D. Burt· 2 shared A. A. Weckel· 1 shared A. E. Tammen· 1 shared A. J. Combes· 1 shared A. K. Aladhami· 1 shared A. M. DeRogatis· 1 shared C. Ekstrand· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

G. K. Fragiadakis

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3 papers

Recent·Most cited

Commensal myeloid crosstalk in neonatal skin regulates cutaneous type 17 inflammation

M. O. Dhariwala, R. O. Carale, A. M. DeRogatis, H. Rodriguez-Valbuena, J. N. Okoro, C. Ekstrand, A. A. Weckel, V. M. Tran, I. Habrylo, R. Barrere-Cain, O. T. Ojewumi, A. E. Tammen, J. Tsui, S. Shaikh, S. Yellamilli, , T. C. Scharschmidt

This study shows that commensal microbes in neonatal skin promote immune homeostasis by regulating monocyte accumulation and IL-17A production by T cells.

bioRxiv · Sep 29, 2023 · PreprintImmunology

Homeostatic cytokines reciprocally modulate the emergence of prenatal effector PLZF+CD4+ T cells in humans

V. Locher, S. Park, D. Bunis, S. Makredes, T. D. Burt, G. K. Fragiadakis, J. Halkias

This study identifies how IL-7 drives the expansion and effector function of prenatal PLZF+ CD4+ T cells in humans, influencing their tissue distribution and differentiation.

bioRxiv · Sep 19, 2022Immunology

CD161 mediates prenatal immune suppression of IFNγ-producing PLZF+ T cells

J. Halkias, E. Rackaityte, D. Aran, V. F. Mendoza, W. L. Eckalbar, T. D. Burt

The paper identifies CD161-mediated suppression of IFNγ-producing PLZF+ T cells in the human fetal intestine, highlighting their role in prenatal immune regulation.

bioRxiv · Apr 21, 2018Immunology