Homeostatic cytokines reciprocally modulate the emergence of prenatal effector PLZF+CD4+ T cells in humans
V. Locher, S. Park, D. Bunis, S. Makredes, T. D. Burt, G. K. Fragiadakis, J. Halkias
This study identifies how IL-7 drives the expansion and effector function of prenatal PLZF+ CD4+ T cells in humans, influencing their tissue distribution and differentiation.
bioRxiv · Sep 19, 2022Immunology