J. Hardy

DNA density is a better indicator of a nuclear bleb than lamin B loss

The paper compares lamin B and DNA levels in nuclear blebs across cell types and perturbations, finding DNA concentration is more consistently reduced than lamin B levels.

Gla-domain mediated targeting of externalized phosphatidylserine for intracellular delivery

This paper describes a GLA-domain that binds externalized phosphatidylserine and enables rapid, energy-independent intracellular delivery of probes in animal models.

Glucocorticoid receptor activation during human microglial differentiation leads to genomic instability and senescence

This study shows that glucocorticoid receptor activation during human microglial differentiation causes genomic instability and senescence, linking early-life stress to neurodevelopmental disorders.

Bacterial Infection of the Placenta Induces Sex-Specific Responses in the Fetal Brain

This study shows that placental infection with Listeria monocytogenes causes sex-specific gene expression changes and neurodevelopmental abnormalities in fetal brains, leading to distinct behavioral outcomes in male and female offspring.

Listeria monocytogenes Infection Alters Extracellular Vesicles Produced by Trophoblast Stem Cells to Confer a Pro-Inflammatory State

This study shows that Listeria monocytogenes infection alters trophoblast stem cell-derived extracellular vesicles, making macrophages pro-inflammatory and more susceptible to infection.