Author

J. Isaacs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Carducci· 2 shared R. Kumar· 2 shared S. Denmeade· 2 shared S. Kachhap· 2 shared A. A. Klammer· 1 shared A. B. Heckert· 1 shared A. Driouchi· 1 shared A. M. De Marzo· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

M. Carducci

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Differential response to LSD1 inhibition in prostate cancer reveals a YAP1 vulnerability in the neuroendocrine subtype

S. Jasim, R. Kumar, S. Kim, T. Krueger, I. Coleman, S. Dalrymple, L. Antony, D. Rosen, B. Hanratty, R. Patel, P. Nelson, Z. Aghaei, J. Beumer, M. Haffner, T. Lotan, , W. Brennen

This paper shows that LSD1 inhibition is effective against neuroendocrine prostate cancer (NEPC) and that combining it with YAP/TEAD inhibition enhances treatment efficacy.

bioRxiv · Jan 17, 2024 · PreprintCancer Biology

Oblique Line Scan Illumination Enables Expansive, Accurate and Sensitive Single Protein Measurements in Solution and in Living Cells

A. Driouchi, M. Bretan, B. J. Davis, A. B. Heckert, M. Seeger, M. Bradley Silva, W. S. Forrest, J. Hsiung, J. Tan, H. Yang, D. T. McSwiggen, L. Song, A. Sule, B. Abaie, B. Conroy, , D. J. Anderson

This paper introduces Oblique Line Scan (OLS) illumination to enhance single-molecule tracking in living cells and solution, enabling high-throughput and sensitive protein dynamics measurements.

bioRxiv · Dec 21, 2023Biophysics

Supraphysiological testosterone induces ferroptosis and activates NF-kappaB mediated immune pathways in prostate cancer through nucleophagy

J. Mendonca, R. Kumar, O. Owoyemi, K. Boyapati, N. Thomas, S. Kanacharoen, M. Coffey, D. Topiwala, C. Gomes, B. Ozbek, T. Jones, M. Rosen, L. Dong, S. Wiens, W. N. Brennen, , S. Kachhap

bioRxiv · Sep 10, 2020 · PreprintCancer Biology