Author

J. Isola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

M. Stout· 2 shared S. Ali Mondal· 2 shared W. M. Freeman· 2 shared A. Schneider· 1 shared B. Miller· 1 shared C. Hubbart· 1 shared H. N. C. Carter· 1 shared J. Alberola-Ila· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

M. Stout

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Author profile →

2 papers

Recent·Most cited

A single-cell atlas of the aging murine ovary

J. Isola, S. R. Ocanas, C. Hubbart, S. Ko, S. Ali Mondal, J. Hense, H. N. C. Carter, A. Schneider, S. Kovats, J. Alberola-Ila, W. M. Freeman, M. Stout

This study creates a single-cell RNA sequencing atlas of aging mouse ovaries, identifying immune cell expansion, collagenase pathway downregulation, and stress/fibrotic signaling in follicular cells.

bioRxiv · Apr 29, 2023 · PreprintCell Biology

17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

S. Ali Mondal, R. Sathiaseelan, S. Mann, M. Kamal, W. Luo, T. Saccon, J. Isola, R. Peeler, T. Li, W. M. Freeman, B. Miller, M. Stout

This study shows that 17-E2 reduces liver fibrosis in male mice by decreasing collagen synthesis and increasing collagen degradation.

bioRxiv · Jun 16, 2022Physiology