Author

R. Sathiaseelan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:rat· 1

Frequent Co-Authors

S. Mann· 3 shared M. Kamal· 2 shared M. Stout· 2 shared S. Ali Mondal· 2 shared W. M. Freeman· 2 shared A. Rothman· 1 shared A. Unnikrishnan· 1 shared B. F. Miller· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersPhysiology

S. Mann

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Author profile →

3 papers

Recent·Most cited

Metabolic benefits of 17α-estradiol in liver are partially mediated by ERβ in male mice

S. Ali Mondal, S. Mann, C. van der Linden, R. Sathiaseelan, M. Kamal, S. Das, M. Bubak, S. Logan, B. F. Miller, M. Stout

This study shows that 17α-estradiol's metabolic benefits in male mice are partially mediated by ERβ in liver, specifically affecting SCD1 and TGF-β1 production.

bioRxiv · Mar 25, 2023 · PreprintPhysiology

17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

S. Ali Mondal, R. Sathiaseelan, S. Mann, M. Kamal, W. Luo, T. Saccon, J. Isola, R. Peeler, T. Li, W. M. Freeman, B. Miller, M. Stout

This study shows that 17-E2 reduces liver fibrosis in male mice by decreasing collagen synthesis and increasing collagen degradation.

bioRxiv · Jun 16, 2022Physiology

Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α

S. Mann, N. Hadad, M. Nelson, A. Rothman, R. Sathiaseelan, S. Ali-Mondal, M.-P. Agbaga, A. Unnikrishnan, S. Malayannan, J. Hawse, D. Huffmam, W. M. Freeman, M. B. Stout

This study shows 17α-estradiol improves metabolic parameters and slows aging in male mice and rats through estrogen receptor α, primarily acting in the liver and hypothalamus.

bioRxiv · Jun 2, 2020Physiology