Author

J. Iyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Research Focus:development & morphogenesis· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

K. F. O'Connell· 2 shared A. Davis· 1 shared A. Naik· 1 shared A. Smith· 1 shared A. Williams· 1 shared B. Bowerman· 1 shared C. Dierlam· 1 shared D. Mathew· 1 shared

Activity by Year

2016-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

K. F. O'Connell

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3 papers

Recent·Most cited

The retromer complex regulates C. elegans development and mammalian ciliogenesis

S. Xie, E. Smith, C. Dierlam, D. Mathew, A. Davis, A. Williams, N. Naslavsky, J. Iyer, S. Caplan

This study shows the retromer complex is essential for C. elegans development and mammalian ciliogenesis, with a role in CP110 removal from the mother centriole.

bioRxiv · Sep 24, 2021Cell Biology

The Chromatin Remodeling Protein CHD-1 and the EFL-1/DPL-1 Transcription Factor Cooperatively Down Regulate CDK-2 to Control SAS-6 Levels and Centriole Number

J. Iyer, L. Gentry, M. Bergwell, A. Smith, S. Guagliardo, P. A. Kropp, P. Sankaralingam, Y. Liu, E. Spooner, B. Bowerman, K. F. O'Connell

This paper shows that CHD-1 and EFL-1/DPL-1 transcription factors reduce CDK-2 expression, which increases SAS-6 levels and centriole number in C. elegans embryos.

bioRxiv · Sep 2, 2021Cell Biology

Protein phosphatase 1 down regulates ZYG-1 levels to limit centrioleduplication

N. Peel, J. Iyer, A. Naik, M. P. Dougherty, M. Decker, K. F. O'Connell

The paper identifies PP1 as a regulator of ZYG-1 levels in C. elegans, showing that reduced PP1 activity increases ZYG-1 and leads to centriole amplification.

bioRxiv · Dec 12, 2016Cell Biology