Author

J. J. Chae

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

a. Belot· 1 shared A. Martin· 1 shared B. Diamond· 1 shared B. Sherry· 1 shared C. Wouters· 1 shared D. Chirita· 1 shared D. Kastner· 1 shared D. L. Kastner· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

a. Belot

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2 papers

Recent·Most cited

Galantamine Attenuates Autoinflammation in a Mouse Model of Familial Mediterranean Fever

I. T. Mughrabi, M. Ochani, M. Tanovic, P. Wang, B. Diamond, B. Sherry, V. Pavlov, S. Ozen, D. L. Kastner, J. J. Chae, Y. Al-Abed

This study shows galantamine reduces inflammation and disease features in a mouse model of familial Mediterranean fever.

bioRxiv · Jun 10, 2022 · PreprintImmunology

Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

F. Magnotti, D. Chirita, S. Dalmon, A. Martin, P. Bronnec, J. Sousa, o. Helynck, W. Lee, D. Kastner, J. J. Chae, M. McDermott, a. Belot, M. Popoff, P. Seve, S. Georgin-Lavialle, , T. Henry

This study identifies steroid hormone catabolites as specific activators of the pyrin inflammasome through a non-canonical mechanism, linking them to autoinflammation and explaining steroid fever.

bioRxiv · Oct 29, 2021Immunology