Author

F. Magnotti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1

Frequent Co-Authors

T. Henry· 2 shared a. Belot· 1 shared A. Martin· 1 shared A. N. Kettenbach· 1 shared C. Wouters· 1 shared D. Chirita· 1 shared D. Kastner· 1 shared E. De Langhe· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

T. Henry

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2 papers

Recent·Most cited

Phosphoprotein Phosphatase Activity Positively Regulates Oligomeric Pyrin to Trigger Inflammasome Assembly in Phagocytes

H. S. Malek, F. Magnotti, N. A. Loeven, J. M. Delgado, A. N. Kettenbach, T. Henry, J. B. Bliska

This study identifies phosphoprotein phosphatase activity as a positive regulator of oligomeric pyrin, essential for inflammasome assembly in phagocytes.

bioRxiv · Mar 23, 2022Immunology

Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

F. Magnotti, D. Chirita, S. Dalmon, A. Martin, P. Bronnec, J. Sousa, o. Helynck, W. Lee, D. Kastner, J. J. Chae, M. McDermott, a. Belot, M. Popoff, P. Seve, S. Georgin-Lavialle, , T. Henry

This study identifies steroid hormone catabolites as specific activators of the pyrin inflammasome through a non-canonical mechanism, linking them to autoinflammation and explaining steroid fever.

bioRxiv · Oct 29, 2021Immunology