The human neuronal receptor NgR1 bridges reovirus capsid proteins to initiate infection
D. M. Sutherland, M. Strebl, M. Koehler, O. L. Welsh, X. Yu, L. Hu, R. dos Santos Natividade, J. J. Knowlton, G. M. Taylor, R. Moreno, P. Woerz, Z. L. Lonergan, P. Aravamudhan, C. Guzman-Cardozo, D. Alsteens, , T. S. Dermody
This study identifies how NgR1 bridges reovirus capsid proteins to initiate infection, revealing a unique binding interface and its role in virus entry and receptor ligand interactions.
bioRxiv · Jul 23, 2021 · PreprintMicrobiology