Author

B. Prasad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1 Cell Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Assay:electrophysiology· 1

Frequent Co-Authors

D. Davydov· 2 shared D. K. Singh· 2 shared G. Yue· 2 shared K. A. Gaither· 2 shared K. Ponraj· 2 shared P. Lazarus· 2 shared A. E. Cetin· 1 shared B. Dangi· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

D. Davydov

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Non-additivity of the functional properties of individual P450 species and its manifestation in the effects of alcohol consumption on the metabolism of ketamine and amitriptyline

K. Ponraj, K. A. Gaither, D. K. Singh, N. Davydova, M. Zhao, S. Luo, P. Lazarus, B. Prasad, D. Davydov

The paper investigates how alcohol affects drug metabolism by analyzing interactions between P450 enzymes in human liver microsomes, finding alcohol increases low-affinity enzyme roles and alters enzyme-specific metabolic rates.

bioRxiv · Jun 14, 2024Biochemistry

Effects of alcohol consumption and tobacco smoking on the composition of the ensemble of drug metabolizing enzymes and transporters in human liver

K. A. Gaither, D. K. Singh, G. Yue, J. Trudeau, K. Ponraj, N. Y. Davydova, P. Lazarus, D. Davydov, B. Prasad

This study investigates how alcohol consumption and smoking affect drug-metabolizing enzymes and transporters in human liver microsomes, identifying significant changes in enzyme abundance and proposing an alcohol exposure index.

bioRxiv · May 14, 2024Pharmacology & Toxicology

IIHP: Intelligent Incident Hypertension Prediction in Obstructive Sleep Apnea

O. Halimi Milani, A. E. Cetin, B. Prasad

This study uses machine learning to predict incident hypertension in OSA patients using polysomnography data, achieving 72% AUC.

bioRxiv · Dec 13, 2023 · PreprintBioengineering

The human neuronal receptor NgR1 bridges reovirus capsid proteins to initiate infection

D. M. Sutherland, M. Strebl, M. Koehler, O. L. Welsh, X. Yu, L. Hu, R. dos Santos Natividade, J. J. Knowlton, G. M. Taylor, R. Moreno, P. Woerz, Z. L. Lonergan, P. Aravamudhan, C. Guzman-Cardozo, D. Alsteens, , T. S. Dermody

This study identifies how NgR1 bridges reovirus capsid proteins to initiate infection, revealing a unique binding interface and its role in virus entry and receptor ligand interactions.

bioRxiv · Jul 23, 2021 · PreprintMicrobiology

Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry

D. R. Davydov, B. Dangi, G. Yue, B. Prasad, V. G. Zgoda

This study uses chemical crosslinking mass spectrometry to identify protein-protein interactions of CYP2E1 in human liver microsomes, revealing its associations with other drug-metabolizing enzymes.

bioRxiv · Jul 2, 2021Biochemistry

Towards customized studies of G-quadruplex DNA structures in live cells

B. Prasad, M. Doimo, M. Andreasson, V. L Hote, E. Chorell, S. Wanrooij

The paper develops a synthetic platform to study G-quadruplex DNA structures in live cells using modified Phen-DC3 compounds with fluorescent and cell-penetrating properties.

bioRxiv · Apr 7, 2021Cell Biology