Author

J. J. Lozano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2

Frequent Co-Authors

B. Aguilar-Bravo· 2 shared C. Foguet· 2 shared L. Zanatto· 2 shared M. Cascante· 2 shared M. Coll· 2 shared P. Sancho-Bru· 2 shared R. A. Martinez Garcia de la Torre· 2 shared S. Affo· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

B. Aguilar-Bravo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis

R. A. Martinez Garcia de la Torre, J. Vallverdu, Z. Xu, S. Arino, B. Aguilar-Bravo, P. Ruiz Blazquez, M. Fernandez Fernandez, A. Navarro-Gascon, A. Blasco-Roset, P. Sanchez--Fernandez-de-Landa, J. Pera Garcia, D. Romero-Moya, P. Ayuso Garcia, C. Martinez Sanchez, L. Zanatto, , P. Sancho-Bru

This study maps the differentiation trajectory of iPSCs to hepatic stellate cells, identifying RORA as a key regulator of metabolic reprogramming and fibrosis.

bioRxiv · Feb 15, 2024Cell Biology

Glutaminase as a metabolic target of choice to counter acquired resistance to Palbociclib by colorectal cancer cells

M. Tarrado-Castellarnau, C. Foguet, J. Tarrago-Celada, M. Palobart, C. Hernandez-Carro, J. Perarnau, E. Zodda, I. H. Polat, S. Marin, A. Suarez-Bonnet, J. J. Lozano, M. Yuneva, T. M. Thomson, M. Cascante

This study shows that combining Palbociclib with Telaglenestat prevents acquired resistance in colorectal cancer cells by counteracting metabolic reprogramming.

bioRxiv · Jan 4, 2024Cancer Biology

Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10

B. D. Lopez-Ayllon, S. Marin, M. Farinas Fernandez, T. Garcia-Garcia, R. Fernandez-Rodriguez, A. de Lucas-Rius, N. Redondo, L. Mendoza-Garcia, C. Foguet, J. Grigas, A. Calvet, J. M. Villalba, M. J. Rodriguez Gomez, D. Megias, B. Mandracchia, , M. Montoya

This study identifies mitochondrial and metabolic reprogramming induced by SARS-CoV-2 accessory proteins in lung cells, revealing potential therapeutic targets.

bioRxiv · Sep 26, 2023Immunology

Hepatocyte Dedifferentiation Profiling In Alcohol-Related Liver Disease Identifies CXCR4 As A Driver Of Cell Reprogramming

B. Aguilar-Bravo, S. Arino, D. Blaya, E. Pose, R. A. Martinez Garcia de la Torre, M. U. Latasa, C. Martinez-Sanchez, L. Zanatto, L. Sererols-Vinas, P. Cantallops, S. Affo, M. Coll, X. Thillen, L. Dubuquoy, M. A. Avila, , P. Sancho-Bru

This study identifies CXCR4 as a driver of hepatocyte dedifferentiation in alcohol-related liver disease through transcriptomic profiling and functional analysis.

bioRxiv · Apr 4, 2023Cell Biology