Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity
A. S. Genshaft, S. Subudhi, A. Keo, J. D. Sanchez Vasquez, N. Conceicao-Neto, D. Mahamed, L. L. Boeijen, N. Alatrakchi, C. Oetheimer, M. Vilme, R. Drake, I. Fleming, N. Tran, C. Tzouanas, J. Joseph-Chazan, , A. Gehring
The paper develops a workflow for collecting and analyzing liver immune cells via fine-needle aspirates and single-cell RNA sequencing to better understand tissue-specific immunity in chronic hepatitis B.
bioRxiv · Nov 30, 2021 · PreprintImmunology