Author

A. Mehrotra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:cell-cell communication· 2 Approach:statistical model· 2 Research Focus:clustering· 1

Frequent Co-Authors

D. Mahamed· 3 shared H. L. A. Janssen· 3 shared S. Nkongolo· 3 shared A. J. Gehring· 2 shared J. J. Feld· 2 shared R. T. Chung· 2 shared A. Boonstra· 1 shared A. Gaggar· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

D. Mahamed

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Author profile →

3 papers

Recent·Most cited

Virus-associated Inflammation Imprints an Inflammatory Profile on Long-lived Monocyte-derived Macrophages in the Human Liver

J.-D. Sanchez, S. Nkongolo, D. Traum, S. C. Kim, D. Mahamed, A. Mehrotra, A. Patel, D. Chen, S. Fung, A. Gaggar, J. J. Feld, K.-M. Chang, J. J. Wallin, H. L. A. Janssen, A. J. Gehring

The paper shows that chronic inflammation in the liver leads to the formation of long-lived inflammatory macrophages derived from monocytes, which retain an inflammatory profile and may drive liver disease progression.

bioRxiv · Jan 31, 2024 · PreprintImmunology

Liver-specific Inflammatory Signatures Predict Clinically Significant Liver Damage.

C. Chua, D. Mahamed, S. Nkongolo, A. Mehrotra, D. K. H. Wong, R. T. Chung, J. J. Feld, H. L. A. Janssen, A. J. Gehring

The paper identifies liver-specific inflammatory signatures that precede clinically significant liver damage in CHB patients after NA withdrawal.

bioRxiv · Feb 28, 2023 · PreprintImmunology

Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity

A. S. Genshaft, S. Subudhi, A. Keo, J. D. Sanchez Vasquez, N. Conceicao-Neto, D. Mahamed, L. L. Boeijen, N. Alatrakchi, C. Oetheimer, M. Vilme, R. Drake, I. Fleming, N. Tran, C. Tzouanas, J. Joseph-Chazan, , A. Gehring

The paper develops a workflow for collecting and analyzing liver immune cells via fine-needle aspirates and single-cell RNA sequencing to better understand tissue-specific immunity in chronic hepatitis B.

bioRxiv · Nov 30, 2021 · PreprintImmunology